Intralesional Therapy

Intralesional Therapy is the injection of a higher concentration of a drug directly into skin lesions without significant systemic absorption.

Most common type of intralesional therapy is intralesional steroid injection.

An intralesional steroid injection involves a corticosteroid such as triamcinolone acetonide injected directly into a lesion on or immediately below the skin.

What are intralesional steroids used for?

An intralesional steroid injection may be indicated for the following skin conditions:

1. Alopecia areata
2. Discoid lupus erythematosus
3. Keloid/hypertrophic scar
4. Granuloma annulare
5. Other granulomatous disorders such as cutaneous sarcoidosis or granuloma faciale
6. Hypertrophic lichen planus
7. Lichen simplex chronicus (neurodermatitis)
8. Localised psoriasis
9. Necrobiosis lipoidica
10. Acne cysts (see nodulocystic acne) and inflamed epidermoid cysts
11. Small infantile haemangiomas
12. Other localised inflammatory skin diseases.